美國(guó)Primary Monkey Podocyte

美國(guó)Primary Monkey Podocyte 猴原代腎足細(xì)胞

美國(guó)PrimCells原代細(xì)胞：PrimCells的原代細(xì)胞產(chǎn)品采用*的高效提取方法， 分離，并通過(guò)盡量縮短體外培養(yǎng)時(shí)間從而保證其更接近體原始狀態(tài)，以適應(yīng)客戶對(duì)細(xì)胞品質(zhì)的嚴(yán)格要求。PrimCells亦是多種腎臟來(lái)源原代細(xì)胞的世界獨(dú)jia供應(yīng)商，為多家藥物研發(fā)企業(yè)提供藥物藥效與毒理測(cè)試。此外，PrimCells還開(kāi)發(fā)出多種轉(zhuǎn)基因胚胎干細(xì)胞、原代胚胎成纖維細(xì)胞等產(chǎn)品，是干細(xì)胞與重編程領(lǐng)域的報(bào)告基因原代細(xì)胞提供商。

Introduction:

Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine¹. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure^{2, 3}.

PrimCells is proud to isolate and provide the primary cultures of podocytes from non-human primates (Macaca Fascicularis, also known as Cynomolgus Macaques) to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.

美國(guó)Primary Monkey Podocyte 猴原代腎足細(xì)胞

美國(guó)PrimCells品牌介紹

PrimCells是位于美國(guó)加州圣迭戈的一家專(zhuān)業(yè)致力于細(xì)胞產(chǎn)品研發(fā)和解決方案提供的業(yè)內(nèi)技術(shù)。

公司匯集了*的生物醫(yī)藥技術(shù)專(zhuān)家，獨(dú)立開(kāi)發(fā)了多項(xiàng)原代細(xì)胞和干細(xì)胞相關(guān)的專(zhuān)有技術(shù)。 公司以“細(xì)胞研究的優(yōu)選擇"為宗旨，自主研發(fā)超過(guò)70種創(chuàng)新產(chǎn)品，多個(gè)特種細(xì)胞市場(chǎng)的空白。例如其誘導(dǎo)性表達(dá)細(xì)胞庫(kù)和高效3D皮膚培養(yǎng)系統(tǒng)，皆為該類(lèi)產(chǎn)品目前市場(chǎng)上少數(shù)的規(guī)模化供應(yīng)商。此外，公司以高質(zhì)量的數(shù)據(jù)與快速穩(wěn)定的項(xiàng)目完成時(shí)間，長(zhǎng)期為多家制藥公司提供解決方案，獲得用戶廣泛贊譽(yù)。

PrimCells產(chǎn)品線：

• 報(bào)告基因干細(xì)胞        2. 原代細(xì)胞（含報(bào)告基因原代細(xì)胞）               3. 誘導(dǎo)性穩(wěn)定細(xì)胞株

4. 人源重組蛋白               5.   創(chuàng)新型培養(yǎng)試劑

PrimCells 解決方案

1.誘導(dǎo)性穩(wěn)定細(xì)胞株開(kāi)發(fā) 2. 原代細(xì)胞開(kāi)發(fā) 3. 藥物體外毒理和效能測(cè)試 4. 3D-皮膚培養(yǎng)

PrimCells合作伙伴及客戶:

A．生物制藥公司：輝瑞(Pfizer), 諾華(Novartis), 禮來(lái)(Eli2  Lilly),. Amgen, EMD Millipore, Regeneron等公司的毒理和醫(yī)藥研發(fā)部門(mén)

B．科研機(jī)構(gòu)：冷泉港實(shí)驗(yàn)室，哈佛醫(yī)學(xué)院, 麻省理工（MIT）,， UCSF, NYU, Salk, UIUC, USC等