美國Primary Rat Podocyte大鼠原代腎足細(xì)胞是美國PrimCells原代細(xì)胞:PrimCells的原代細(xì)胞產(chǎn)品采用*的高效提取方法, 分離,并通過盡量縮短體外培養(yǎng)時間從而保證其更接近體原始狀態(tài),以適應(yīng)客戶對細(xì)胞品質(zhì)的嚴(yán)格要求。PrimCells亦是多種腎臟來源原代細(xì)胞的世界獨JIA供應(yīng)商,為多家藥物研發(fā)企業(yè)提供藥物藥效與毒理測試。此外,PrimCells還開發(fā)出多種轉(zhuǎn)基因胚胎干細(xì)胞、原代胚胎成纖維細(xì)胞等產(chǎn)品,是干細(xì)胞與重編程領(lǐng)域的報告基因原代細(xì)胞提供商。
Species:
Sprague Dawley
Catalog Number:
PCKDR01
Cell Number:
~1x106
Storage/Shipping:
Freshly Isolated
Introduction:
Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.
PrimCells is proud to isolate and provide the primary cultures of podocytes from Sprague Dawley rats to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.